Ramin Shiekhattar

Roles

• Academic Director of the Oncogenomic Core Facility


• Chief of Division of Cancer Genomics and Epigenetics


• Director of the Cancer Epigenetics Research Program


• Professor, Biochemistry & Molecular Biology


• Professor, Dr. John T. Macdonald Foundation Department of Human Genetics

Research Interests

 My laboratory has made a number of important contributions over the past several years in identifying and characterizing critical mediators of epigenome. These include a number of chromatin remodeling (human NURF, CERF, WCRF/ACF) and chromatin modifyingUTX/MLL3/4, JARID1d, LSD1-CoREST complexes. Importantly, the emerging roles for non-coding RNAs in epigenetic regulation and their crosstalk with chromatin regulatory complexes persuaded us to characterize the key players in the biogenesis and effector function of non-coding RNAs.