Luciana Rodrigues

Affiliations:

2010 – PhD, Cellular and Molecular Biology, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, RJ, Brazil; 

2010-2013 – Post-Doc, Laboratory of Cellular Microbiology, Oswaldo Cruz Institute (IOC), Rio de Janeiro, RJ, Brazil; 

2012-2012 – Post-Doctoral studies in Global Health Institute, École Polytechnique Fédérale de Lausanne, Switzerland;

2013 – Professor at Medical Sciences Faculty, Rio de Janeiro State University (UERJ, Universidade do Estado do Rio de Janeiro), Rio de Janeiro, RJ, Brazil; professor of the Postgraduate Program in Medical Sciences (PGCM / UERJ) and coordinator of the Laboratory of Immunopathology (LIP / UERJ).

Lines of Research:

Immunology, Microbiology, Cellular and Molecular Biology, interaction of mycobacteria with the host cell, development and application of diagnostic tests for Tuberculosis, as well as definition of exposition (latent infection) biomarkers and active disease.

Published Articles:

1. LISBOA, VINÍCIUS DA CUNHA; RIBEIRO-ALVES, MARCELO; CORRÊA, RAQUEL DA SILVA; LOPES, ISABELLE RAMOS; MAFORT, THIAGO THOMAZ; SANTOS, ANA PAULA GOMES DOS; AMADEU, THAÍS PORTO; RUFINO, ROGÉRIO; Rodrigues, Luciana Silva

The predominance of Th1 Immune Response in Pleural Effusion of Patients with Tuberculosis Among Other Exudative Etiologies. JOURNAL OF CLINICAL MICROBIOLOGY. , v.58, p.e00927-19 - , 2020.

2. LOPES, MARIANA CARNEIRO; AMADEU, THAÍS PORTO; RIBEIRO-ALVES, MARCELO; DA COSTA, CLAUDIA HENRIQUE; Rodrigues, Luciana Silva; BESSA, ELISABETH JAUHAR CARDOSO; BRUNO, LEONARDO PALERMO; LOPES, AGNALDO JOSÉ; RUFINO, ROGERIO

Identification of Active Sarcoidosis Using Chitotriosidase and Angiotensin-Converting Enzyme. LUNG. , v.197, p.295 - 302, 2019.

3. SILVA, R. J.; CORREA, R. S.; SARDELLA, I. G.; MULINARI, A. C. P.; MAFORT, T. T.; SANTOS, A. P.; RUFINO, R.; Rodrigues, L.S.; SAAD, M. H. F.

IgA and IgG antibody detection of mycobacterial antigens in pleural fluid and serum from pleural tuberculous patients. BMC IMMUNOLOGY. , v.20, p.36 - , 2019.

4. TERRA, RODRIGO; ALVES, PEDRO J. F.; LIMA, ANA K. C.; GOMES, SHAYANE M. R.; Rodrigues, Luciana S.; SALERNO, VERÔNICA P.; DA-SILVA, SILVIA A. G.; DUTRA, PATRICIA M. L.

Immunomodulation From Moderate Exercise Promotes Control of Experimental Cutaneous Leishmaniasis. Frontiers in Cellular and Infection Microbiology. , v.9, p.115 - , 2019.

5. CORRÊA, RAQUEL DA SILVA; Rodrigues, Luciana Silva; PEREIRA, LETICIA HAGGE LIMA; NOGUEIRA, OTTO CASTRO; LEUNG, JANAÍNA; SOUSA, MARCELA DA S; HACKER, MARIANA DE ANDREA; SIQUEIRA, HELIO RIBEIRO DE; CAPONE, DOMÊNICO; ALVES, ROGÉRIO LOPES RUFINO; Pessolani, Maria Cristina Vidal; SCHMITZ, VERONICA; PEREIRA, GERALDO MOURA BATISTA

Neutrophil CD64 expression levels in IGRA-positive individuals distinguish latent tuberculosis from active disease. Memórias do Instituto Oswaldo Cruz. , v.114, p.e180579 - , 2019.

6. AMORIM, RENATA F.; VIEGAS, EDUARDO R. C.; CARNEIRO, ANTONIO JOSÉ V.; ESBERARD, BARBARA C.; CHINEM, EVELYN S.; CORREA, RAQUEL S.; RODRIGUES, LUCIANA; RIBEIRO-ALVES, MARCELO; SILVA, KELLY S.; DE SOUZA, HEITOR S.; CARVALHO, ANA TERESA P.

Superiority of Interferon Gamma Assay Over Tuberculin Skin Test for Latent Tuberculosis in Inflammatory Bowel Disease Patients in Brazil. DIGESTIVE DISEASES AND SCIENCES. , v.64, p.1916 - 1922, 2019.

7. SANTOS, ANA PAULA; CORRÊA, RAQUEL DA SILVA; RIBEIRO-ALVES, MARCELO; SOARES DA SILVA, ANA CAROLINA OLIVEIRA; MAFORT, THIAGO THOMAZ; LEUNG, JANAÍNA; PEREIRA, GERALDO MOURA BATISTA; Rodrigues, Luciana Silva; RUFINO, ROGÉRIO

Application of Venn's diagram in the diagnosis of pleural tuberculosis using IFN-γ, IP-10 and adenosine deaminase. PLoS One. , v.13, p.e0202481 - , 2018.

8. DÍAZ ACOSTA, CHYNTIA CAROLINA; DIAS, ANDRÉ ALVES; ROSA, THABATTA LEAL SILVEIRA ANDREZO; BATISTA-SILVA, LEONARDO RIBEIRO; ROSA, PATRICIA SAMMARCO; TOLEDO-PINTO, THIAGO GOMES; COSTA, FABRÍCIO DA MOTA RAMALHO; LARA, FLÁVIO ALVES; Rodrigues, Luciana Silva; MATTOS, KATHERINE ANTUNES; Sarno, Euzenir Nunes; BOZZA, PATRÍCIA TORRES; GUILHOT, CHRISTOPHE; DE BERRÊDO-PINHO, MÁRCIA; Pessolani, Maria Cristina Vidal

PGL I expression in live bacteria allows activation of a CD206/PPARγ cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves. PLoS Pathogens. , v.14, p.e1007151 - , 2018.

9. DE CARVALHO, FERNANDA MARQUES; Rodrigues, Luciana Silva; DUPPRE, NÁDIA CRISTINA; ALVIM, IRIS MARIA PEIXOTO; RIBEIRO-ALVES, MARCELO; PINHEIRO, ROBERTA OLMO; Sarno, Euzenir Nunes; Pessolani, Maria Cristina Vidal; PEREIRA, GERALDO MOURA BATISTA

Interruption of persistent exposure to leprosy combined or not with recent BCG vaccination enhances the response to Mycobacterium leprae specific antigens. PLoS Neglected Tropical Diseases. , v.11, p.e0005560 - , 2017.

10. SCHMITZ, V.; PRATA, R. B. S.; BARBOZA, M. G. M.; MENDES, M. A.; BRANDAO, S. S.; Amadeu, TP; Rodrigues, L.S.; COSTA, F. M. R.; SANTOS, J. B.; PACHECO, F. S.; MIRANDA, A.; Nery, JAC; HACKER, M. V. B.; SALES, A. M.; Pinheiro, R.O.; SARNO, E. N.

Expression of CD64 on Circulating Neutrophils Favoring Systemic Inflammatory Status in Erythema Nodosum Leprosum. PLoS Neglected Tropical Diseases (Online). , v.10, p.e0004955 - , 2016.

11. SILVA, L. R. B.; Rodrigues, L.S.; VIVARINI, A. C.; COSTA, F. M. R.; Mattos, K.A.; Costa, M.R.S.N.; ROSA, P. S.; DE TOLEDO-PINTO, THIAGO GOMES; Dias, AA; MOURA, D. F.; SARNO, E. N.; LOPES, U. G.; PESSOLANI, M. C. V.

Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages. Scientific Reports. , v.6, p.27632 - , 2016.

12. DE TOLEDO-PINTO, THIAGO GOMES; FERREIRA, ANNA BEATRIZ ROBOTTOM; RIBEIRO-ALVES, MARCELO; Rodrigues, Luciana Silva; BATISTA-SILVA, LEONARDO RIBEIRO; SILVA, BRUNO JORGE DE ANDRADE; LEMES, ROBERTHA MARIANA RODRIGUES; MARTINEZ, ALEJANDRA NÓBREGA; SANDOVAL, FELIPE GALVAN; ALVARADO-ARNEZ, LUCIA ELENA; ROSA, PATRÍCIA SAMMARCO; SHANNON, EDWARD JOSEPH; Pessolani, Maria Cristina Vidal; PINHEIRO, ROBERTA OLMO; ANTUNES, SÉRGIO LUÍS GOMES; Sarno, Euzenir Nunes; LARA, FLÁVIO ALVES; WILLIAMS, DIANA LYNN; OZÓRIO MORAES, MILTON

STING-Dependent 2´-5´ Oligoadenylate Synthetase-Like Production Is Required for Intracellular Mycobacterium leprae Survival. The Journal of Infectious Diseases. , v.214, p.jiw144 - , 2016.

13. MEDEIROS, RYCHELLE CLAYDE AFFONSO; VASCONCELOS, KARINA GIRARDI DO CARMO DE; CARDOSO, FERNANDA KARLLA LUZ; MIETO, BRUNO DE SIQUEIRA; PINTO, THIAGO GOMES DE TOLEDO; GOMEZ, LILIAN SALES; Rodrigues, Luciana Silva; GANDINI, MARIANA; AMARAL, JULIO JABLONSKI; ANTUNES, SÉRGIO LUIZ GOMES; CORTE-REAL, SUZANA; ROSA, PATRICIA SAMMARCO; Pessolani, Maria Cristina Vidal; NERY, JOSÉ AUGUSTO DA COSTA; Sarno, Euzenir Nunes; SILVA, LEONARDO RIBEIRO BATISTA; SOLA-PENNA, MAURO; OLIVEIRA, MARCUS FERNANDES DE; MORAES, MILTON OZÓRIO; LARA, FLAVIO ALVES

Subversion of Schwann Cell Glucose Metabolism by Mycobacterium leprae. The Journal of Biological Chemistry (Print). , v.1, p.jbc.M116.725283 - , 2016.

14. SILVA, C. A. M.; DANELISHVILI, L.; MCNAMARA, M.; MOREIRA, M. B. P.; BILDFELL, R.; BIET, F.; RODRIGUES, L. S.; OLIVEIRA, A. V.; BERMUDEZ, L. E.; PESSOLANI, M. C. V.; PESSOLANI, M. C. V.

Interaction of Mycobacterium leprae with human airway epithelial cells: adherence, entry, survival and identification of potential adhesins by surface proteome analysis. Infection and Immunity (Print). , v.81, p.000 - , 2013.

15. Rodrigues, Luciana Silva; Hacker, Mariana Andrea; Illarramendi, Ximena; Pinheiro, Maria Fernanda Miguens Castelar; da Costa Nery, Jose Augusto; Sarno, Euzenir Nunes; Pessolani, Maria Cristina Vidal

Circulating levels of Insulin-like Growth Factor-I (IGF-I) correlate with disease status in leprosy. BMC Infectious Diseases (Online). , v.11, p.339 - , 2011.

16. Mattos, K.A.; Lara, Flavio A.; Oliveira, V.G.C.; Rodrigues, L.S.; D´Ávilla, H.; Melo, Rossana C. N.; Manso, Pedro P. A.; SARNO, E. N.; Bozza, P.T.; Pessolani, Maria Cristina V.

Modulation of lipid droplets by Mycobacterium leprae in Schwann cells: a putative mechanism for host lipid acquisition and bacterial survival in phagosomes. Cellular Microbiology (Print). , v.13, p.259 - 273, 2011.

17. Mattos, K. A.; Oliveira, V. G. C.; D'Avila, H.; RODRIGUES, L. S.; Pinheiro, R. O.; SARNO, E. N.; PESSOLANI, M. C. V.; Bozza, P. T.

TLR6-Driven Lipid Droplets in Mycobacterium leprae-Infected Schwann Cells: Immunoinflammatory Platforms Associated with Bacterial Persistence. The Journal of Immunology (1950). , v.187, p.2548 - 2558, 2011.

18. RODRIGUES, L. S.; Mattos, K.A.; D'Ávilla, H.; Oliveira, V.G.C.; SARNO, E. N.; Atella, G.C.; Pereira, G.M.; Bozza, P.T.; PESSOLANI, M. C. V.

Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis. Journal of Leukocyte Biology. , v.87, p.371 - 384, 2010.

19. Rodrigues, Luciana Silva; RIBEIRO-RESENDE, VICTOR TÃ'ºLIO; ROSSLE, SHAILA; ALVES, LUCINEIA; LOPES, ULISSES GAZOS; LOBATO, LÃ'­VIA SILVA; TEMPONE, ANTONIO JORGE; MOREIRA, MARIA ELISABETE COSTA; DA SILVA MAEDA, ELISA; Pessolani, Maria Cristina Vidal

Mycobacterium leprae induces insulin-like growth factor and promotes survival of Schwann cells upon serum withdrawal. Cellular Microbiology (Print). , v.12, p.42 - 54, 2010.